FlyBase Allele Report: Dmel\Phf7[UASp.cYa]

General Information

Symbol

Dmel\Phf7^UASp.cYa

Species

D. melanogaster

Name

FlyBase ID

FBal0277259

Feature type

allele

Associated gene

Dmel\Phf7

Associated Insertion(s)

Carried in Construct

P{UASp-Phf7.Y}

Key Links

Transgenic product class

cDNA

(Yang et al., 2012)

wild_type

(Yang et al., 2012)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Yang et al., 2012)

wild_type

(Yang et al., 2012)

Mutagen

in vitro construct

(Yang et al., 2012)

Progenitor genotype

Carried in construct

P{UASp-Phf7.Y}

Cytology

Description

UASp regulatory sequences drive expression of the full-length Phf7 cDNA clone LD43541.

(Yang et al., 2012)

Allele components

Component

Use(s)

Regulatory region(s)

UASp

binary expression system - regulatory region

Encoded product / tool

Phf7

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased cell number | oogenesis, with Scer\GAL4^{VP16.nanos.UTR}

(Yang, 2021)

Phenotype Manifest In

female germline cell | absent, with Scer\GAL4^{VP16.nanos.UTR}

(Yang, 2021)

Detailed Description

Statement

Reference

Expression of Phf7^{Scer\UAS.P\T.cYa} under the control of Scer\GAL4^{nos.UTR.T:Hsim\VP16} results in loss of the female germline.

(Yang et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Phf7^UASp.cYa, Scer\GAL4^{VP16.nanos.UTR} has decreased cell number | oogenesis phenotype, enhanceable by HP1D3csd[+]/HP1D3csd^f07323

(Yang, 2021)

Phf7^UASp.cYa, Scer\GAL4^{VP16.nanos.UTR} has decreased cell number | oogenesis phenotype, enhanceable by HP1D3csd^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^{VP16.nanos.UTR}

(Yang, 2021)

Phf7^UASp.cYa, Scer\GAL4^{VP16.nanos.UTR} has decreased cell number | oogenesis phenotype, enhanceable by Df(1)ED7441/+

(Yang, 2021)

tra¹/Df(3L)st-j7, Phf7^UASp.cYa, Scer\GAL4^{VP16.nanos.UTR} has abnormal sex-determination | female phenotype, enhanceable by HP1D3csd[+]/HP1D3csd^f07323

(Yang, 2021)

Suppressed by

Statement

Reference

tra¹/Df(3L)st-j7, Phf7^UASp.cYa, Scer\GAL4^{VP16.nanos.UTR} has abnormal sex-determination | female phenotype, suppressible | partially by HP1D3csd^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^{VP16.nanos.UTR}

(Yang, 2021)

Suppressor of

Statement

Reference

Scer\GAL4^{VP16.nanos.UTR}/Phf7^UASp.cYa is a suppressor | partially of abnormal sex-determination | female phenotype of tra¹/Df(3L)st-j7

(Yang, 2021)

Other

Statement

Reference

tra¹/Df(3L)st-j7, Phf7^UASp.cYa, Scer\GAL4^{VP16.nanos.UTR} has abnormal sex-determination | female phenotype

(Yang, 2021)

Phenotype Manifest In

Enhanced by

Statement

Reference

Phf7^UASp.cYa, Scer\GAL4^{VP16.nanos.UTR} has female germline cell | absent phenotype, enhanceable by HP1D3csd[+]/HP1D3csd^f07323

(Yang, 2021)

Phf7^UASp.cYa, Scer\GAL4^{VP16.nanos.UTR} has female germline cell | absent phenotype, enhanceable by HP1D3csd^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^{VP16.nanos.UTR}

(Yang, 2021)

Phf7^UASp.cYa, Scer\GAL4^{VP16.nanos.UTR} has female germline cell | absent phenotype, enhanceable by Df(1)ED7441/+

(Yang, 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^{VP16.nanos.UTR}/Phf7^UASp.cYa rescues Phf7^ΔN2

(Yang et al., 2017)

Phf7^UASp.cYa rescues Phf7^ΔN2

(Yang et al., 2012)

Phf7^UASp.cYa rescues Phf7^ΔN18

(Yang et al., 2012)

Comments

The expression of Phf7^{Scer\UAS.P\T.cYa} under the control of Scer\GAL4^{nos.UTR.T:Hsim\VP16} rescues the fecundity defects of Phf7^ΔN2 homozygous males.

(Yang et al., 2017)

Basal expression of Phf7^{Scer\UAS.P\T.cYa} (in the absence of a Scer\GAL4 driver) rescues the reduced fecundity of Phf7^ΔN2 and Phf7^ΔN18 males.

(Yang et al., 2012)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Phf7^{Scer\UAS.P\T.cYa}

Phf7^UASp.cYa

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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