FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\14-3-3εUAS.Tag:FLAG
Open Close
General Information
Symbol
Dmel\14-3-3εUAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0277318
Feature type
allele
Associated gene
Dmel\14-3-3ε
Associated Insertion(s)
Carried in Construct
P{UAS-14-3-3ε.FLAG}
Key Links
Transgenic product class
wild_type
(Yang and Terman, 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Yang and Terman, 2012)
Mutagen
in vitro construct
(Yang and Terman, 2012)
Progenitor genotype
Carried in construct
P{UAS-14-3-3ε.FLAG}
Cytology
Description

UAS regulatory sequences drive expression of 14-3-3ε which is tagged with Tag:FLAG.

(Yang and Terman, 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
14-3-3ε
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of 14-3-3εScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4elav.PU results in axon guidance defects in the ISNb nerve, which are characterised by increased bundling and fasciculation.

      (Yang and Terman, 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The axon guidance defects in the central nervous system which are caused by expression of plexAScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4elav.PU are suppressed if the embryos also co-express 14-3-3εScer\UAS.T:Zzzz\FLAG.

      (Yang and Terman, 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4NP1301/14-3-3εUAS.Tag:FLAG partially rescues 14-3-3εj2B10/14-3-3εNP1301

      (Yang and Terman, 2012)
      Comments

      The ISNb and SNa axon guidance defects seen in 14-3-3εj2B10/14-3-3εNP1301 embryos are partially suppressed by expression of 14-3-3εScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL414-3-3ε-NP1301.

      (Yang and Terman, 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      14-3-3εScer\UAS.T:Zzzz\FLAG
      14-3-3εUAS.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (1)