FB2026_02 , released June 18, 2026
Allele: Dmel\Mgat1UAS.cSa
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General Information
Symbol
Dmel\Mgat1UAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Sarkar
FlyBase ID
FBal0277324
Feature type
allele
Associated gene
Dmel\Mgat1
Associated Insertion(s)
Carried in Construct
P{UAS-Mgat1.S}
Also Known As
UAS-Mgat1
Key Links
Transgenic product class
cDNA
(Sarkar et al., 2010)
wild_type
(Sarkar et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Sarkar et al., 2010)
wild_type
(Sarkar et al., 2010)
Mutagen
in vitro construct
(Sarkar et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-Mgat1.S}
Cytology
Description

UASt regulatory sequences drive expression of a Mgat1 cDNA.

(Sarkar et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Mgat1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Larvae expressing Mgat1Scer\UAS.cSa under the control of Scer\GAL4He.PZ are able to encapsulate eggs of the avirulent wasp L. clavipes, as occurs in wild-type larvae.

      Larvae expressing Mgat1Scer\UAS.cSa under the control of Scer\GAL4He.PZ are able to encapsulate eggs of the LvPhil, LvHaw and LvUnk strains of the parasitic wasp L. victoriae at a high frequency, in contrast to wild-type larvae which fail to encapsulate eggs of these strains.

      Larvae expressing Mgat1Scer\UAS.cSa under the control of Scer\GAL4He.PZ are not able to encapsulate eggs of the wasp L. heterotoma.

      (Mortimer et al., 2012)

      Expression of Mgat1Scer\UAS.cSa under the control of Scer\GAL4elav.Switch.PO in the presence of RU486 results in an increase in mean and maximum lifespan (8% and 13% respectively).

      Flies expressing Mgat1Scer\UAS.cSa under the control of Scer\GAL4elav.Switch.PO in the presence of RU486 are significantly more resistant to hydrogen peroxide than control flies.

      (Sarkar et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4elav.Switch.PO/Mgat1UAS.cSa partially rescues Mgat11

      (Sarkar et al., 2010)
      Comments

      Expression of Mgat1Scer\UAS.cSa under the control of Scer\GAL4elav.Switch.PO in the presence of RU486 rescues the shortened lifespan of Mgat11 adults. The rescued flies are significantly more resistant to hydrogen peroxide than Mgat11 mutant flies. The rescued flies have significantly lower locomotor activity than wild type.

      (Sarkar et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Mgat1Scer\UAS.cSa
      Mgat1UAS.cSa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Sarkar
      Secondary FlyBase IDs
        References (2)