FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\slprPXAP.UASp.Tag:HA
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General Information
Symbol
Dmel\slprPXAP.UASp.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0277699
Feature type
allele
Associated gene
Dmel\slpr
Associated Insertion(s)
Carried in Construct
P{UASp-slpr.PXAP}
Key Links
Transgenic product class
missense_variant
(Gonda et al., 2012)
polypeptide_post_translational_processing_variant
(Gonda et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Gonda et al., 2012)
polypeptide_post_translational_processing_variant
(Gonda et al., 2012)
Mutagen
in vitro construct
(Gonda et al., 2012)
Progenitor genotype
slprUASp.Tag:HA
(Gonda et al., 2012)
Carried in construct
P{UASp-slpr.PXAP}
Cytology
Description

Amino acid replacement S512A, resulting in a non-phosphorylatable form of slpr.

(Gonda et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
slpr
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of slprPXAP.Scer\UAS.P\T.T:Ivir\HA1 under the control of Scer\GAL4pnr-MD237 does not result in a failure of dorsal closure in embryos.

      Expression of slprPXAP.Scer\UAS.P\T.T:Ivir\HA1 under the control of Scer\GAL4pnr-MD237 results in narrowing of the scutellum and loss of scutellar bristles.

      Male flies expressing slprPXAP.Scer\UAS.P\T.T:Ivir\HA1 under the control of Scer\GAL4arm.PS and raised at 25[o]C show significantly decreased survival on exposure to 37[o]C heat shock compared to wild-type controls.

      Embryos expressing slprPXAP.Scer\UAS.P\T.T:Ivir\HA1 under the control of Scer\GAL4arm.PS show significantly increased lethality on exposure to 37[o]C heat shock compared to wild-type controls.

      (Gonda et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      slprPXAP.UASp.Tag:HA/Scer\GAL4arm.PS rescues slprBS06

      (Gonda et al., 2012)
      Comments

      Expression of slprPXAP.Scer\UAS.P\T.T:Ivir\HA1 under the control of Scer\GAL4arm.PS significantly rescues the lethality of slprBS06 animals.

      (Gonda et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      slprPXAP.Scer\UAS.P\T.T:Ivir\HA1
      slprPXAP.UASp.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)