FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Hsap\ATF3UAS.Tag:FLAG
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General Information
Symbol
Hsap\ATF3UAS.Tag:FLAG
Species
H. sapiens
Name
FlyBase ID
FBal0277814
Feature type
allele
Associated gene
Hsap\ATF3
Associated Insertion(s)
Carried in Construct
P{UAS-hATF3.FLAG}
Key Links
Transgenic product class
cDNA
(Rynes et al., 2012)
wild_type
(Rynes et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Rynes et al., 2012)
wild_type
(Rynes et al., 2012)
Mutagen
in vitro construct
(Rynes et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-hATF3.FLAG}
Cytology
Description

UASt regulatory sequences drive expression of a Hsap\ATF3 cDNA which is tagged at the C-terminal end with Tag:FLAG.

(Rynes et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\ATF3
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Scer\GAL4fat/Hsap\ATF3UAS.Tag:FLAG is a suppressor | partially of lethal phenotype of Atf376

      (Rynes et al., 2012)

      Scer\GAL4C7/Hsap\ATF3UAS.Tag:FLAG is a suppressor | partially of lethal phenotype of Atf376

      (Rynes et al., 2012)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Scer\GAL4fat/Hsap\ATF3UAS.Tag:FLAG is a suppressor | partially of lipid droplet phenotype of Atf376

      (Rynes et al., 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of Hsap\ATF3Scer\UAS.T:Zzzz\FLAG under the control of either Scer\GAL4fat or Scer\GAL4C7 significantly improves the survival of Atf376/Y males.

      Expression of Hsap\ATF3Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4fat rescues the abnormally large lipid droplets and high triacylglycerol levels seen in Atf376 larvae.

      (Rynes et al., 2012)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Hsap\ATF3Scer\UAS.T:Zzzz\FLAG
      Hsap\ATF3UAS.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (1)