FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\CysGMR.PK
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General Information
Symbol
Dmel\CysGMR.PK
Species
D. melanogaster
Name
FlyBase ID
FBal0277938
Feature type
allele
Associated gene
Dmel\Cys
Associated Insertion(s)
Carried in Construct
P{GMR-Cys.K}
Key Links
Transgenic product class
cDNA
(Kinser and Dolph, 2012)
wild_type
(Kinser and Dolph, 2012)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Kinser and Dolph, 2012)
wild_type
(Kinser and Dolph, 2012)
Mutagen
in vitro construct
(Kinser and Dolph, 2012)
Progenitor genotype
Carried in construct
P{GMR-Cys.K}
Cytology
Description

A Cys coding cDNA is placed under the control of eye-specific GMR promoter sequence.

(Kinser and Dolph, 2012)
Allele components
Component
Use(s)
Regulatory region(s)
GMR
Encoded product / tool
Cys
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      CysGMR.PK is a suppressor of eye phenotype of car1

      (Kinser and Dolph, 2012)

      CysGMR.PK is a suppressor of ommatidium phenotype of car1

      (Kinser and Dolph, 2012)

      CysGMR.PK is a suppressor of rhabdomere phenotype of car1

      (Kinser and Dolph, 2012)

      CysGMR.PK is a suppressor of eye phenotype of norpAEE5

      (Kinser and Dolph, 2012)

      CysGMR.PK is a suppressor of rhabdomere phenotype of norpAEE5

      (Kinser and Dolph, 2012)

      CysGMR.PK is a suppressor of ommatidium phenotype of norpAEE5

      (Kinser and Dolph, 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of CysGMR in norpA7 mutants fully rescues the retinal degeneration seen upon exposure to constant light for 6 days. This rescue is robust and provides protection when light exposure is extended to 8 days.

      The presence of CysGMR rescues the retinal degeneration seen in car1 after 9-days of constant light.

      (Kinser and Dolph, 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CysGMR.PK
      CysGMR
      Name Synonyms
      Secondary FlyBase IDs
        References (1)