FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\foxoUAS.cLa
Open Close
General Information
Symbol
Dmel\foxoUAS.cLa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Lee
FlyBase ID
FBal0278192
Feature type
allele
Associated gene
Dmel\foxo
Associated Insertion(s)
Carried in Construct
P{UAS-foxo.L}
Key Links
Transgenic product class
wild_type
(Lee and Chung, 2007)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Lee and Chung, 2007)
Mutagen
in vitro construct
(Lee and Chung, 2007)
Progenitor genotype
Carried in construct
P{UAS-foxo.L}
Cytology
Description

UASt regulatory sequences drive expression of full-length foxo.

(Lee and Chung, 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
foxo
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of foxoScer\UAS.cLa under the control of Scer\GAL4GMR.PU results in a reduction in eye size with ommatidial loss.

      (Lee and Chung, 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      Scer\GAL4GMR.PU, foxoUAS.cLa has visible phenotype, enhanceable by rictorΔ24

      (Lee and Chung, 2007)

      Scer\GAL4GMR.PU, foxoUAS.cLa has visible phenotype, enhanceable by rictorΔ42

      (Lee and Chung, 2007)
      Suppressed by
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The reduction in eye size and ommatidial loss caused by expression of foxoScer\UAS.cLa under the control of Scer\GAL4GMR.PU is dramatically enhanced in a rictorΔ24 or rictorΔ42 background.

      Co-expression of rictorScer\UAS.T:Zzzz\FLAG almost completely suppresses the reduction in eye size and ommatidial loss caused by expression of foxoScer\UAS.cLa under the control of Scer\GAL4GMR.PU.

      (Lee and Chung, 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      foxoScer\UAS.cLa
      foxoUAS.cLa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Lee
      Secondary FlyBase IDs
        References (1)