FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Diap1UY1835
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General Information
Symbol
Dmel\Diap1UY1835
Species
D. melanogaster
Name
FlyBase ID
FBal0278259
Feature type
allele
Associated gene
Dmel\Diap1
Associated Insertion(s)
P{Mae-UAS.6.11}Diap1UY1835
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{Mae-UAS.6.11}Diap1UY1835
    Cytology
    Description

    Insertion at +2088bp from the transcription start site of the B transcript of Diap1, in the correct orientation to allow overexpression of Diap1 from the Scer\UAS sites in the inserted element.

    (Marchal et al., 2012)
    Allele components
    Component
    Use(s)
    Inserted element
    P{Mae-UAS.6.11}
    Regulatory region(s)
    UAS
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 1 )
        Disease
        Interaction
        References
        ameliorates  human immunodeficiency virus infectious disease
        modeled by HIV-1\VpuUAS.cLa
        (Marchal et al., 2012)
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        NOT Suppressor of
        Statement
        Reference

        Diap1UY1835, Scer\GAL4GMR.PFa is a non-suppressor of visible phenotype of HIV-1\VpuUAS.cLa, Scer\GAL4GMR.PFa

        (Marchal et al., 2012)
        Phenotype Manifest In
        Suppressor of
        NOT Suppressor of
        Statement
        Reference

        Diap1UY1835, Scer\GAL4GMR.PFa is a non-suppressor of eye phenotype of HIV-1\VpuUAS.cLa, Scer\GAL4GMR.PFa

        (Marchal et al., 2012)
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference

        Co-expression of thUY1835 suppresses the wing defects caused by expression of HIV-1\VpuScer\UAS.cLa under the control of Scer\GAL4dpp.blk1 but does not suppress the eye defects caused by expression of HIV-1\VpuScer\UAS.cLa under the control of Scer\GAL4GMR.PFa. The increased cell death seen in wing discs of animals expressing HIV-1\VpuScer\UAS.cLa under the control of Scer\GAL4dpp.blk1 are also suppressed by thUY1835.

        (Marchal et al., 2012)
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        Diap1UY1835
        thUY1835
        Name Synonyms
        Secondary FlyBase IDs
          References (1)