FlyBase Allele Report: Dmel\sgg[HMS01751]

General Information

Symbol

Dmel\sgg^HMS01751

Species

D. melanogaster

Name

FlyBase ID

FBal0278869

Feature type

allele

Associated gene

Dmel\sgg

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS01751}

Also Known As

sgg RNAi, UAS-sgg-IR, sgg-RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS01751}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS01751

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates amyotrophic lateral sclerosis type 6

modeled by Hsap\FUS^UAS.cBa

(Tziortzouda et al., 2024)

modeled by Hsap\FUS^{R521G.UAS.cBa}

(Tziortzouda et al., 2024)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female sterile, with Scer\GAL4^{VP16.mat.αTub67C}

(Sopko et al., 2014)

lethal, with Scer\GAL4^e22c

(Trostnikov et al., 2019)

lethal, with Scer\GAL4^elav-C155

(Trostnikov et al., 2019)

lethal, with Scer\GAL4^ppl.PP

(Trostnikov et al., 2019)

short lived | female, with Scer\GAL4^Mef2.PR

(Trostnikov et al., 2019)

short lived | male, with Scer\GAL4^Mef2.PR

(Trostnikov et al., 2019)

Phenotype Manifest In

embryo | maternal effect, with Scer\GAL4^{VP16.mat.αTub67C}

(Sopko et al., 2014)

Detailed Description

Statement

Reference

Females heterozygous for sgg^HMS01751 and Scer\GAL4^{mat.αTub67C.T:Hsim\VP16} crossed to sgg^HMS01751 males results in: 0% hatching; egg/embryonic phenotype: "all white, no development"; maternal effect.

(Sopko et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

sgg^HMS01751/Scer\GAL4^bab1-Gal4 is a suppressor | partially of abnormal cell number | oogenesis phenotype of Scer\GAL4^bab1-Gal4, piwi^KK105350

(Lin et al., 2020)

Phenotype Manifest In

Suppressor of

Statement

Reference

sgg^HMS01751/Scer\GAL4^bab1-Gal4 is a suppressor | partially of female germline stem cell phenotype of Scer\GAL4^bab1-Gal4, piwi^KK105350

(Lin et al., 2020)

sgg^HMS01751/Scer\GAL4^bab1-Gal4 is a suppressor | partially of germarium phenotype of Scer\GAL4^bab1-Gal4, piwi^KK105350

(Lin et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

38293

y¹ sc^* v¹ sev²¹; P{TRiP.HMS01751}attP40

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

sgg^HMS01751

Name Synonyms

Secondary FlyBase IDs

References (15)

Report Sections

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