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General Information
Symbol
Dmel\shrbHMS01767
Species
D. melanogaster
Name
FlyBase ID
FBal0278885
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
HMS01767
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of a short inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of shrbHMS01767 under the control of Scer\GAL4nos.PG results in a number of defects in the female germline stem cells (GSCs). Approximately 45% of the GSCs form 'stem cysts' in which they are interconnected to several daughter cells (both linear and branched chains of cells are seen) and approximately 10% of the GSCs are polyploid. Approximately 50% of the egg chambers contain 32 germ cells.

More than 50% of egg chambers contain 32 cells in females expressing shrbHMS01767 under the control of Scer\GAL4nos.PG. In these egg chambers, the oocyte is linked to the nurse cells by 5 ring canals. Approximately 50% of germaria contain 'stem cysts' in which the female germline stem cells are interconnected to daughter cells. The cells in these stem cysts undergo synchronous division.

Egg chambers containing 32 cells are seen in females expressing shrbHMS01767 under the control of Scer\GAL4nos.PG in the presence of Scer\GAL80bam.PM.

Females expressing shrbHMS01767 under the control of Scer\GAL4bam.T:Hsim\VP16 have egg chambers containing the normal number of 16 cells.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
shrbHMS01767
Name Synonyms
Secondary FlyBase IDs
    References (5)