FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Syx5UAS.Tag:MYC
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General Information
Symbol
Dmel\Syx5UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0280611
Feature type
allele
Associated gene
Dmel\Syx5
Associated Insertion(s)
Carried in Construct
P{UAS-Syx5.myc}
Key Links
Transgenic product class
wild_type
(Norgate et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Norgate et al., 2010)
Mutagen
in vitro construct
(Norgate et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-Syx5.myc}
Cytology
Description

UASt regulatory sequences drive expression of a Tag:MYC-tagged Syx5.

(Norgate et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Syx5
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of Syx5Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4pnr-MD237 results in reduced scutellum and bristles, but no change in pigmentation.

      Flies co-expressing Syx5GD1743 and Syx5Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4pnr-MD237 show decreased pigmentation.

      (Norgate et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Phenotype Manifest In
      Enhanced by
      NOT Enhanced by
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of Ctr1AGD16726 under the control of Scer\GAL4pnr-MD237 exacerbates the Syx5GD1743-induced hypopigmentation in flies also expressing Syx5Scer\UAS.T:Hsap\MYC.

      Overexpression of Ctr1AScer\UAS.cBa.T:Zzzz\FLAG fails to suppress the hypopigmentation of flies also expressing bot Syx5Scer\UAS.T:Hsap\MYC and Syx5GD1743 under the control of Scer\GAL4pnr-MD237.

      (Norgate et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Syx5Scer\UAS.T:Hsap\MYC
      Syx5UAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (3)