FlyBase Allele Report: Dmel\stai[exC]

General Information

Symbol

Dmel\stai^exC

Species

D. melanogaster

Name

FlyBase ID

FBal0280810

Feature type

allele

Associated gene

Dmel\stai

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Borghese et al., 2006)

Progenitor genotype

P{GSV1}stai^GS2209

(Borghese et al., 2006)

Cytology

Description

Imprecise excision of the progenitor insertion, resulting in a deletion that removes the first two exons of the stai C transcript. This mutation leaves the stai A and B isoforms intact.

(Borghese et al., 2006)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

fertile

(Borghese et al., 2006)

viable

(Borghese et al., 2006)

Phenotype Manifest In

border follicle cell (with Df(2L)stai^L27), with Scer\GAL4^slbo.2.6, stai^RNAi.UAS.WIZ

(Borghese et al., 2006)

Detailed Description

Statement

Reference

Homozygous and stai^exC/Df(2L)stai^L27 females show no defects in border cell migration.

Females expressing stai^{dsRNA.Scer\UAS.WIZ} under the control of Scer\GAL4^slbo.2.6 in a stai^exC/Df(2L)stai^L27 background show defects in border cell migration.

(Borghese et al., 2006)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

The delay in border cell migration seen in females expressing stai^{dsRNA.Scer\UAS.WIZ} under the control of Scer\GAL4^slbo.2.6 in a stai^exC/Df(2L)stai^L27 background are rescued by co-expression of stai^Scer\UAS.cBa.

(Borghese et al., 2006)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Stathmin^ExC

(Borghese et al., 2006)

stai^exC

stathmin^exC

(Borghese et al., 2006)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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