FB2026_02 , released June 18, 2026
Allele: Dmel\sosie4
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General Information
Symbol
Dmel\sosie4
Species
D. melanogaster
Name
FlyBase ID
FBal0280914
Feature type
allele
Associated gene
Dmel\sosie
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
minos activity
(Urwyler et al., 2012)
Progenitor genotype
Mi{ET1}sosieMB03846
(Urwyler et al., 2012)
Caused by aberration
Df(3R)sosie4
Cytology
Description

Imprecise excision of the progenitor insertion, resulting in a deletion that removes the 3 most C-terminal sosie exons and part of the neighbouring CG33658 gene.

(Urwyler et al., 2012)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous females contain compound egg chambers containing 2 germ-line cysts. These defects can be seen in early egg chambers (stages 4-5). Egg chambers with discontinuous follicle epithelia are seen in all stages of oogenesis after the cysts have left the germarium. Apical F-actin accumulation appears normal in follicle cells.

      (Urwyler et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      cherunspecified/sosie4 double heterozygotes show delayed migration of the border cells relative to the outer follicle cells and irregular actin in more than 60% of egg chambers.

      chicunspecified/sosie4 double heterozygotes often have egg chamber packaging defects and egg chambers often have irregular actin. Delayed migration of the border cells relative to the outer follicle cells is seen in more than 60% of egg chambers.

      (Urwyler et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      sie4
      (Urwyler et al., 2012)
      sosie4
      Name Synonyms
      Secondary FlyBase IDs
        References (1)