FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\for11.247
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General Information
Symbol
Dmel\for11.247
Species
D. melanogaster
Name
FlyBase ID
FBal0282007
Feature type
allele
Associated gene
Dmel\for
Associated Insertion(s)
P{GawB}for11.247
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - molecular evidence

Mutagen
    Nature of the Allele
    Allele class

    hypomorphic allele - molecular evidence

    (Eddison et al., 2012)
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GawB}for11.247
    Cytology
    Description

    Insertion within for, 994bp downstream of exon 1.

    (Eddison et al., 2012)
    Allele components
    Component
    Use(s)
    Inserted element
    P{GawB}
    Encoded product / tool
    GAL4
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Mutant flies show a normal initial olfactory startle response to a pulse of ethanol vapour, but show enhanced habituation of the olfactory startle response compared to wild-type controls.

        (Eddison et al., 2012)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        for11.247 is rescued by forUAS.T1/Scer\GAL4for-11.247

        (Eddison et al., 2012)
        Comments

        Expression of forScer\UAS.T1 under the control of Scer\GAL4for-11.247 rescues the enhanced habituation of the olfactory startle response which is seen in for11.247 flies.

        (Eddison et al., 2012)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        Comments
        Comments

        Precise excision of the insertion reverts the abnormal habituation phenotype.

        (Eddison et al., 2012)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        11.247
        (Eddison et al., 2012)
        for11.247
        (Song et al., 2019)
        Name Synonyms
        Secondary FlyBase IDs
          References (2)