FB2026_02 , released June 18, 2026
Allele: Dmel\Bacc537m
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General Information
Symbol
Dmel\Bacc537m
Species
D. melanogaster
Name
FlyBase ID
FBal0282676
Feature type
allele
Associated gene
Dmel\Bacc
Associated Insertion(s)
P{}Bacc537m
Carried in Construct
Key Links
Allele class

hypomorphic allele - molecular evidence

Mutagen
    Nature of the Allele
    Allele class

    hypomorphic allele - molecular evidence

    (Chen et al., 2013)
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{}Bacc537m
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Homozygous females show reduced sensitivity to ethanol intoxication compared to wild type (tested with 45% ethanol). Homozygous males show reduced sensitivity to ethanol intoxication compared to wild type at 35% and 40% ethanol, but not at 45% ethanol.

        Feeding with tyramine, but not with octopamine, largely restores normal ethanol sensitivity in homozygous flies.

        (Chen et al., 2013)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        Bacc537m is rescued by BaccCH322-08H15

        (Chen et al., 2013)
        Comments

        BaccCH322-08H15 rescues the ethanol insensitivity Bacc537m/Bacc537m flies.

        (Chen et al., 2013)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Bacc537m
        (Chen et al., 2013)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)