FB2026_02 , released June 18, 2026
Allele: Dmel\AldoUAS.cMa
Open Close
General Information
Symbol
Dmel\AldoUAS.cMa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Miller
FlyBase ID
FBal0283005
Feature type
allele
Associated gene
Dmel\Aldo
Associated Insertion(s)
Carried in Construct
P{UAS-Aldo.M}
Key Links
Transgenic product class
cDNA
(Miller et al., 2012)
wild_type
(Miller et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Miller et al., 2012)
wild_type
(Miller et al., 2012)
Mutagen
in vitro construct
(Miller et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-Aldo.M}
Cytology
Description

UAS regulatory sequences drive expression of the Ald B isoform (cDNA clone LD37852).

(Miller et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Aldo
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4Tub.PU/AldoUAS.cMa partially rescues Aldom4

      (Miller et al., 2012)

      Scer\GAL4elav-C155/AldoUAS.cMa partially rescues Aldom4

      (Miller et al., 2012)

      Scer\GAL4repo-M1B/AldoUAS.cMa partially rescues Aldom4

      (Miller et al., 2012)
      Comments

      Expression of AldScer\UAS.cMa under the control of Scer\GAL4tub.PU fully rescue the temperature sensitive paralysis phenotype and significantly (but not completely) rescues the lifespan and neurodegeneration defects of Aldm4 homozygotes.

      Expression of AldScer\UAS.cMa under the control of Scer\GAL4repo-M1B does not rescue the shortened lifespan of Aldm4 homozygotes, while the neurodegeneration defect is substantially rescued.

      Expression of AldScer\UAS.cMa under the control of Scer\GAL4elav-C155 significantly (but not completely) rescues the shortened lifespan and substantially rescues the neurodegeneration defects of Aldm4 homozygotes.

      (Miller et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      Ald1UAS.cMa
      AldScer\UAS.cMa
      AldUAS.cMa
      AldoUAS.cMa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Miller
      Secondary FlyBase IDs
        References (1)