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FB2026_01
,
released March 12, 2026
Ald, Ald1, Aldolase 1
Please see the JBrowse view of Dmel\Aldo for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.43
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.49
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
360 (aa)
Homotetramer.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Aldo using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Glycolytic enzymes, including Gpdh1 protein are localized to M bands and Z discs, as visualized in the isolated myofibrils of flight muscles, where immunoreactivity appears as alternating bright and less-intense bands.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Aldo in JBrowsePlease Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Area matching Drosophila Fructose 1,6 bisphosphare aldolase gene, Acc. No. M98351.
At least a substantial fraction of three glycolytic enzymes of flight muscle cells are found colocalised at the Z-discs and M-lines, glycolytic enzyme colocalisation is interdependent. Localisation of Gapdh1, Gapdh2 and Ald at the Z-discs and M-lines requires the presence of at least Gpdh at the Z-discs and M-lines.
The structural gene for aldolase (fructose-biphosphate aldolase).
Source for merge of: Ald BcDNA:LP07735
Source for merge of Ald BcDNA:LP07735 was a shared cDNA ( date:030728 ).
Source for identity of: Ald1 Ald
Source for identity of: Aldo Ald1
Renamed from 'Aldolase 1' (Ald1) to 'Aldolase' (Aldo) because (i) it is the only Aldolase paralog encoding a catalytically active enzyme, and (ii) 'Aldo' is the more commonly used symbol for this gene across species.
Renamed from 'Ald' to 'Ald1' in recognition that there's a second Aldolase gene (Ald2/CG5432).
