FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\apt13-66
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General Information
Symbol
Dmel\apt13-66
Species
D. melanogaster
Name
FlyBase ID
FBal0284924
Feature type
allele
Associated gene
Dmel\apt
Associated Insertion(s)
P{GawB}apt13-66
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GawB}apt13-66
    Cytology
    Description

    Insertion 295bp upstream of the apt-RA transcription start site.

    (McClure and Heberlein, 2013)
    Allele components
    Component
    Use(s)
    Inserted element
    P{GawB}
    Encoded product / tool
    GAL4
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Mutant flies show a dramatic reduction in ethanol sedation sensitivity compared to wild type.

        The gross morphology of the central nervous system is normal in mutant flies.

        (McClure and Heberlein, 2013)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Fails to complement

        apt167

        (McClure and Heberlein, 2013)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        Comments
        Comments

        Precise excision of the insertion completely reverts the reduced ethanol sedation sensitivity phenotype.

        (McClure and Heberlein, 2013)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        apt13-66
        (McClure and Heberlein, 2013)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)