FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tyfΔC5.UAS.Tag:V5
Open Close
General Information
Symbol
Dmel\tyfΔC5.UAS.Tag:V5
Species
D. melanogaster
Name
FlyBase ID
FBal0285121
Feature type
allele
Associated gene
Dmel\tyf
Associated Insertion(s)
Carried in Construct
P{UAS-tyf.ΔC5.V5}
Key Links
Transgenic product class
inframe_deletion
(Lim and Allada, 2013)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Lim and Allada, 2013)
Mutagen
in vitro construct
(Lim and Allada, 2013)
Progenitor genotype
Carried in construct
P{UAS-tyf.ΔC5.V5}
Cytology
Description

UAS regulatory sequences drive expression of mutant tyf lacking the Atx2-binding domain. The construct is tagged at the C-terminal end with Tag:V5.

(Lim and Allada, 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
tyf
Tagged with
Tag:V5
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of tyfΔC5.Scer\UAS.T:SV5\V5 under the control of Scer\GAL4Mz520 leads to aberrant long-period circadian locomotor rhythm under free-running constant dark conditions.

      (Lee et al., 2017)

      Flies expressing tyfΔC5.Scer\UAS.T:SV5\V5 under the control of Scer\GAL4P2.4.Pdf exhibit locomotor rhythm defects. This phenotype is seen is all insertion lines analysed.

      (Lim and Allada, 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The aberrant long-period circadian locomotor rhythm under free-running constant dark conditions characteristic for adult flies expressing tyfΔC5.Scer\UAS.T:SV5\V5 under the control of Scer\GAL4Mz520 is enhanced by co-expression of Lsm12HMS01143 but not me31BNIG.4916R.

      (Lee et al., 2017)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      tyfΔC5.UAS.Tag:V5/Scer\GAL4P2.4.Pdf fails to rescue tyfΔG14151

      (Lim and Allada, 2013)

      tyfΔC5.UAS.Tag:V5/Scer\GAL4P2.4.Pdf fails to rescue tyfe00614

      (Lim and Allada, 2013)
      Comments

      Expression of tyfΔC5.Scer\UAS.T:SV5\V5 under the control of Scer\GAL4P2.4.Pdf fails to rescue the locomotor rhythm defects seen in tyfΔG14151 mutant flies.

      Expression of tyfΔC5.Scer\UAS.T:SV5\V5 under the control of Scer\GAL4P2.4.Pdf fails to rescue the locomotor rhythm defects seen in tyfe00614 mutant flies.

      (Lim and Allada, 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      tyfΔC5.Scer\UAS.T:SV5\V5
      tyfΔC5.UAS.Tag:V5
      Name Synonyms
      Secondary FlyBase IDs
        References (2)