FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\stckD303V.Tag:FLAG
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General Information
Symbol
Dmel\stckD303V.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0285284
Feature type
allele
Associated gene
Dmel\stck
Associated Insertion(s)
Carried in Construct
P{stck-FLAG.D303V}
Key Links
Transgenic product class
missense_variant
(Pronovost et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Pronovost et al., 2013)
Mutagen
in vitro construct
(Pronovost et al., 2013)
Progenitor genotype
stckwt.Tag:FLAG
(Pronovost et al., 2013)
Carried in construct
P{stck-FLAG.D303V}
Cytology
Description

Amino acid replacement: D303V.

(Pronovost et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
stck
Encoded product / tool
stck
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      stck3R-17/stck18 adults rescued by stckD303V.T:Zzzz\FLAG are recovered at 90% of the expected frequency. The rescued adults frequently have wing blisters and wings are often seen in a "held up" position.

      Expression of stckD303V.T:Zzzz\FLAG in an otherwise wild-type background has no effect on larval size.

      (Pronovost et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      flwG0172 mutants carrying stckD303V.T:Zzzz\FLAG arrest during the larval stages. The larvae are significantly smaller and significantly less motile than flwG0172 single mutant larvae. Expression of stckD303V.T:Zzzz\FLAG slightly rescues the detachment of ventral intersegmental muscles seen in flwG0172 larvae.

      (Pronovost et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      stckD303V.Tag:FLAG partially rescues stck18/stck3R-17

      (Pronovost et al., 2013)
      Comments

      stck3R-17/stck18 adults rescued by stckD303V.T:Zzzz\FLAG are recovered at 90% of the expected frequency.

      (Pronovost et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      stckD303V.T:Zzzz\FLAG
      stckD303V.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (2)