UASt regulatory sequences drive expression of a mutant form of Atac2 in which the C-terminal HAT domain has been deleted.
intestinal stem cell, with Scer\GAL4NP5130
The midguts of flies expressing Atac2ΔHAT.Scer\UAS.cMa under the control of Scer\GAL4esg-NP5130 contain many small intestinal stem cell (ISC)-like cell clusters, rather than the single or paired cells seen in controls.