FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\numbRNAi.UAS.THU1674
Open Close
General Information
Symbol
Dmel\numbRNAi.UAS.THU1674
Species
D. melanogaster
Name
FlyBase ID
FBal0287573
Feature type
allele
Associated gene
Dmel\numb
Associated Insertion(s)
Carried in Construct
P{UAS-numb.RNAi.THU1674}
Key Links
Transgenic product class
RNAi_reagent
(Zhou and Luo, 2013)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Zhou and Luo, 2013)
Mutagen
in vitro construct
(Zhou and Luo, 2013)
Progenitor genotype
Carried in construct
P{UAS-numb.RNAi.THU1674}
Cytology
Description

UAS regulatory sequences drive expression of a numb RNAi construct.

(Zhou and Luo, 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
numb
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of numbdsRNA.Scer\UAS.THU1674 under the control of Scer\GAL4c768 results in overgrowth of the neuroepithelium in the third larval instar optic lobe.

      (Zhou and Luo, 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of numbdsRNA.Scer\UAS.THU1674 significantly rescues the loss of neuroepithelium cells seen in the optic lobe of third instar larvae expressing RPA3GD4799 under the control of Scer\GAL4c768.

      (Zhou and Luo, 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      numbRNAi.UAS.THU1674
      numbdsRNA.Scer\UAS.THU1674
      numbdsRNA.UAS.THU1674
      Name Synonyms
      Secondary FlyBase IDs
        References (2)