FlyBase Allele Report: Dmel\arr::dsh[DIX-ctail.UAS]

General Information

Symbol

Dmel\arr::dsh^{DIX-ctail.UAS}

Species

D. melanogaster

Name

FlyBase ID

FBal0288701

Feature type

allele

Associated gene

arr::dsh

Associated Insertion(s)

Carried in Construct

P{UAS-dsh.DIX.ctail}

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Metcalfe et al., 2010)

Progenitor genotype

Carried in construct

P{UAS-dsh.DIX.ctail}

Cytology

Description

UAS regulatory sequences drive expression of a polymerization-defective version of the dsh DIX domain fused at the C-terminus with the cytoplasmic tail of arr.

(Metcalfe et al., 2010)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

arr::dsh

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

embryonic/first instar larval cuticle, with Scer\GAL4^arm.PS

(Metcalfe et al., 2010)

embryonic/first instar larval cuticle, with Scer\GAL4^arm.PS, dsh³

(Metcalfe et al., 2010)

ventral denticle belt, with Scer\GAL4^arm.PS

(Metcalfe et al., 2010)

ventral denticle belt, with Scer\GAL4^arm.PS, dsh³

(Metcalfe et al., 2010)

Detailed Description

Statement

Reference

Expression of dsh^{DIX.Scer\UAS.T:ctail-arr} under the control of Scer\GAL4^arm.PS produces embryos with completely naked cuticles.

Expression of dsh^{DIX.Scer\UAS.T:ctail-arr} in dsh³ mutants under the control of Scer\GAL4^arm.PS produces embryos with completely naked cuticles.

(Metcalfe et al., 2010)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

NOT suppressed by

Statement

Reference

Scer\GAL4^arm.PS, arr::dsh^{DIX-ctail.UAS} has ventral denticle belt phenotype, non-suppressible by arr²

(Metcalfe et al., 2010)

Scer\GAL4^arm.PS, arr::dsh^{DIX-ctail.UAS} has embryonic/first instar larval cuticle phenotype, non-suppressible by arr²

(Metcalfe et al., 2010)

NOT Enhancer of

Statement

Reference

Scer\GAL4^arm.PS/arr::dsh^{DIX-ctail.UAS} is a non-enhancer of ventral denticle belt phenotype of pan³

(Metcalfe et al., 2010)

Scer\GAL4^arm.PS/arr::dsh^{DIX-ctail.UAS} is a non-enhancer of embryonic/first instar larval cuticle phenotype of pan³

(Metcalfe et al., 2010)

NOT Suppressor of

Statement

Reference

Scer\GAL4^arm.PS/arr::dsh^{DIX-ctail.UAS} is a non-suppressor of ventral denticle belt phenotype of pan³

(Metcalfe et al., 2010)

Scer\GAL4^arm.PS/arr::dsh^{DIX-ctail.UAS} is a non-suppressor of embryonic/first instar larval cuticle phenotype of pan³

(Metcalfe et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of dsh^{DIX.Scer\UAS.T:ctail-arr} in arr² mutants under the control of Scer\GAL4^arm.PS produces embryos with completely naked cuticles.

pan³ mutant embryos exhibit the same denticle lawn phenotype irrespective of the presence or absence of Scer\GAL4^arm.PS>dsh^{DIX.Scer\UAS.T:ctail-arr}.

(Metcalfe et al., 2010)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

arr::dsh^{DIX-ctail.Scer\UAS}

arr::dsh^{DIX-ctail.UAS}

dsh^{DIX.Scer\UAS.T:ctail-arr}

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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