FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ry609N
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General Information
Symbol
Dmel\ry609N
Species
D. melanogaster
Name
FlyBase ID
FBal0290208
Feature type
allele
Associated gene
Dmel\ry
Associated Insertion(s)
Carried in Construct
M{ry.609N}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(McMahan et al., 2013)
Progenitor genotype
ry+t7.2
(McMahan et al., 2013)
ry609
(McMahan et al., 2013)
Carried in construct
M{ry.609N}
Cytology
Description

The mutation present in ry609 (nucleotide substitution G3506A) has been introduced by site-directed mutagenesis. The following additional nucleotide substitutions have also introduced by site-directed mutagenesis: G-2914C (destroys a PstI site), C1103G and C1106T (these two changes together destroy a PstI site), A2950G (destroys a BamHI site), C3358G (destroys a SphI site), A3511T (creates a BglI site together with the ry609 G3506A mutation), C3610A (creates an EcoRI site), A3735C (creates a BamHI site), insertion of GATATCGAATT at +4163 (inserts EcoRV and EcoRI sites), C4169G (destroys a NheI site) and C6998G (destroys an AgeI site). (Coordinates follow the system of FBrf0044473, in which +1 is within an EcoRI site in the second exon. This corresponds to nucleotide 3R:8859890 on the release 5 genome.)

(McMahan et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
ry
Encoded product / tool
ry
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      ry609N partially rescues ry506

      (McMahan et al., 2013)
      Comments

      ry609N rescues wild-type eye colour but not survival on purine selection in ry506 flies.

      (McMahan et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ry609N
      (McMahan et al., 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)