FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tslUAS.cJa
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General Information
Symbol
Dmel\tslUAS.cJa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Johnson
FlyBase ID
FBal0290719
Feature type
allele
Associated gene
Dmel\tsl
Associated Insertion(s)
Carried in Construct
M{UAS-tsl.J}
Also Known As
UAS-tsl
Key Links
Transgenic product class
cDNA
(Johnson et al., 2013)
wild_type
(Johnson et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Johnson et al., 2013)
wild_type
(Johnson et al., 2013)
Mutagen
in vitro construct
(Johnson et al., 2013)
Progenitor genotype
Carried in construct
M{UAS-tsl.J}
Cytology
Description

UASt regulatory sequences drive expression of tsl cDNA.

(Johnson et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
tsl
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of tslScer\UAS.cJa under the control of Scer\GAL4c355 results in embryos with a spliced cuticle phenotype (the terminal regions are expanded at the expense of terminal segments).

      (Henstridge et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of trkScer\UAS.P\T.T:Ivir\HA1,T:Hsap\MYC under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 has no effect on the embryonic cuticle phenotype caused by expression of tslScer\UAS.cJa under the control of Scer\GAL4c355.

      (Henstridge et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      tslUAS.cJa/Scer\GAL4da-BG00643 rescues tslΔ

      (Johnson et al., 2013)
      Fails to rescue

      tslUAS.cJa/Scer\GAL4phtm.PO fails to rescue tslΔ

      (Johnson et al., 2013)
      Comments

      Expression of tslScer\UAS.cJa under the control of Scer\GAL4da-BG00643 rescues the delay in pupariation seen in tslΔ mutants. Expression of tslScer\UAS.cJa under the control of Scer\GAL4phm.PO is unable to rescue the phenotype.

      (Johnson et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      tslScer\UAS.cJa
      tslUAS.cJa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Johnson
      Secondary FlyBase IDs
        References (4)