FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\PtthUASp.Tag:HA
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General Information
Symbol
Dmel\PtthUASp.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0290721
Feature type
allele
Associated gene
Dmel\Ptth
Associated Insertion(s)
Carried in Construct
P{UASp-Ptth.HA}
Also Known As
UAS-ptth
Key Links
Transgenic product class
wild_type
(Johnson et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Johnson et al., 2013)
Mutagen
in vitro construct
(Johnson et al., 2013)
Progenitor genotype
Carried in construct
P{UASp-Ptth.HA}
Cytology
Description

UASp regulatory sequences drive expression of the Ptth coding sequence, including introns, tagged at the C-terminal end with Tag:HA.

(Johnson et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
Ptth
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of PtthScer\UAS.P\T.T:Ivir\HA1 under the control of Scer\GAL4phm.PO results in a marked advancement in the time of pupariation compared with controls. Male body size is reduced. When PtthScer\UAS.P\T.T:Ivir\HA1 is expressed in the germ line under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 the patterning of the embryonic cuticle is grossly disrupted.

      (Johnson et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      PtthUASp.Tag:HA, Scer\GAL4phtm.PO has abnormal size phenotype, enhanceable by tslΔ

      (Johnson et al., 2013)
      NOT suppressed by
      Statement
      Reference

      PtthUASp.Tag:HA, Scer\GAL4phtm.PO has abnormal developmental rate phenotype, non-suppressible by tslΔ

      (Johnson et al., 2013)
      Phenotype Manifest In
      NOT suppressed by
      Statement
      Reference

      PtthUASp.Tag:HA, Scer\GAL4VP16.nanos.UTR has embryo phenotype, non-suppressible by tslΔ

      (Johnson et al., 2013)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      A tslΔ mutant background does not suppress the advanced pupariation phenotype seen in flies expressing PtthScer\UAS.P\T.T:Ivir\HA1 under the control of Scer\GAL4phm.PO. The decrease in male body size is further enhanced. The embryonic patterning defects seen when PtthScer\UAS.P\T.T:Ivir\HA1 is expressed under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 are also not suppressed.

      (Johnson et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      PtthScer\UAS.P\T.T:Ivir\HA1
      PtthUASp.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (2)