FlyBase Allele Report: Dmel\Leash[UAS.cKa]

General Information

Symbol

Dmel\Leash^UAS.cKa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Kwon

FlyBase ID

FBal0293736

Feature type

allele

Associated gene

Dmel\Leash

Associated Insertion(s)

Carried in Construct

P{UAS-Leash.K}

Key Links

Transgenic product class

wild_type

(Kwon et al., 2013)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Kwon et al., 2013)

Mutagen

in vitro construct

(Kwon et al., 2013)

Progenitor genotype

Carried in construct

P{UAS-Leash.K}

Cytology

Description

5xUAS regulatory sequences drive expression of the full-length coding sequence of Leash.

(Kwon et al., 2013)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Leash

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size, with Scer\GAL4^en.PU

(Kwon et al., 2013)

Phenotype Manifest In

wing, with Scer\GAL4^en.PU

(Kwon et al., 2013)

Detailed Description

Statement

Reference

Overexpression of Scer\GAL4^en.PU>Leash^Scer\UAS.cKa results in reduced wing size compared with controls.

(Kwon et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL80^ts.αTub84B, Leash^UAS.cKa, Scer\GAL4^NP5130 is a suppressor of increased cell number phenotype of Scer\GAL4^NP5130, Scer\GAL80^ts.αTub84B, yki^{S111A.S168A.S250A.UAS.Tag:V5}

(Kwon et al., 2013)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL80^ts.αTub84B, Leash^UAS.cKa, Scer\GAL4^NP5130 is a suppressor of intestinal stem cell of posterior adult midgut epithelium phenotype of Scer\GAL4^NP5130, Scer\GAL80^ts.αTub84B, yki^{S111A.S168A.S250A.UAS.Tag:V5}

(Kwon et al., 2013)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Leash^Scer\UAS.cKa

Leash^UAS.cKa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Kwon

Secondary FlyBase IDs

References (1)

Report Sections

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