FlyBase Allele Report: Dmel\Ubi-p63E[23b]

General Information

Symbol

Dmel\Ubi-p63E^23b

Species

D. melanogaster

Name

FlyBase ID

FBal0294229

Feature type

allele

Associated gene

Dmel\Ubi-p63E

Associated Insertion(s)

P{?EPgy2}Ubi-p63E^23b

Carried in Construct

Key Links

Allele class

amorphic allele - molecular evidence

amorphic allele - genetic evidence

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

amorphic allele - genetic evidence

(Lu et al., 2013)

amorphic allele - molecular evidence

(Lu et al., 2013)

Mutagen

Delta2-3 transposase

(Lu et al., 2013)

Progenitor genotype

P{EPgy2}Ubi-p63E^EY07341

(Lu et al., 2013)

Associated Insertion(s)

P{?EPgy2}Ubi-p63E^23b

Cytology

Description

Imprecise excision of P{EPgy2}Ubi-p63E^EY07341, resulting in retention of a 43bp fragment of the starting element in the Ubi-p63E 5' UTR.

(Lu et al., 2013)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal meiotic cell cycle | male limited (with Ubi-p63E^12c)

(Lu et al., 2013)

abnormal meiotic cell cycle | male limited (with Ubi-p63E^Z3-2534)

(Lu et al., 2013)

abnormal meiotic cell cycle | male limited (with Ubi-p63E^Z3-3969)

(Lu et al., 2013)

abnormal meiotic cell cycle | male limited (with Ubi-p63E^Z3-4216)

(Lu et al., 2013)

abnormal meiotic cell cycle | male limited (with Ubi-p63E^Z3-5802)

(Lu et al., 2013)

female fertile (with Ubi-p63E^12c)

(Lu et al., 2013)

male sterile (with Ubi-p63E^12c)

(Lu et al., 2013)

viable (with Ubi-p63E^12c)

(Lu et al., 2013)

Phenotype Manifest In

testis (with Ubi-p63E^12c)

(Lu et al., 2013)

testis (with Ubi-p63E^Z3-2534)

(Lu et al., 2013)

testis (with Ubi-p63E^Z3-3969)

(Lu et al., 2013)

testis (with Ubi-p63E^Z3-4216)

(Lu et al., 2013)

testis (with Ubi-p63E^Z3-5802)

(Lu et al., 2013)

Detailed Description

Statement

Reference

Ubi-p63E^12c/Ubi-p63E^23b flies are fully viable, develop at a normal pace to adulthood and females are robustly fertile.

(Lu et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Ubi-p63E^23b/Ubi-p63E^12c is rescued by Ubi-p63E^+tLa

(Lu et al., 2013)

Ubi-p63E^23b is rescued by Ubi-p63E^+tLa

(Lu et al., 2013)

Comments

Ubi-p63E^+tLa completely rescues the meiotic arrest seen in Ubi-p63E^12c/Ubi-p63E^23b testes.

Ubi-p63E^+tLa completely rescues the meiotic arrest and male sterility of Ubi-p63E^23b.

(Lu et al., 2013)

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

61503

y¹ w^*; Ubi-p63E^23b/TM3, Sb¹

Notes on Origin

Discoverer

Separable from: A secondary lethal mutation.

(Lu et al., 2013)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Ubi-p63E^23b

magn^23b

(Lu et al., 2013)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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