FlyBase Allele Report: Dmel\Slik[HMC03770]

General Information

Symbol

Dmel\Slik^HMC03770

Species

D. melanogaster

Name

FlyBase ID

FBal0294330

Feature type

allele

Associated gene

Dmel\Slik

Associated Insertion(s)

Carried in Construct

P{TRiP.HMC03770}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMC03770}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMC03770

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal larval locomotory behavior, with Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

abnormal size | larval stage, with Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

decreased rate of adult locomotory behavior, with Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

short lived, with Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Phenotype Manifest In

larval ventral nerve cord, with Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

NMJ bouton | larval stage, with Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^elav.PLu, Slik^HMC03770 has abnormal size | larval stage phenotype, suppressible by Hsap\SLK^UAS.cAa, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has abnormal larval locomotory behavior phenotype, suppressible by Hsap\SLK^UAS.cAa, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has decreased rate of adult locomotory behavior phenotype, suppressible by Hsap\SLK^UAS.cAa, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

NOT suppressed by

Statement

Reference

Scer\GAL4^elav.PLu, Slik^HMC03770 has abnormal size | larval stage phenotype, non-suppressible by Hsap\SLK^E472term.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has abnormal size | larval stage phenotype, non-suppressible by Hsap\SLK^S781Y.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has decreased rate of adult locomotory behavior phenotype, non-suppressible by Hsap\SLK^Q538term.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has decreased rate of adult locomotory behavior phenotype, non-suppressible by Hsap\SLK^S781Y.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has abnormal size | larval stage phenotype, non-suppressible by Hsap\SLK^R1037G.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has abnormal size | larval stage phenotype, non-suppressible by Hsap\SLK^Q538term.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has abnormal larval locomotory behavior phenotype, non-suppressible by Hsap\SLK^E472term.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has abnormal larval locomotory behavior phenotype, non-suppressible by Hsap\SLK^Q538term.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has abnormal larval locomotory behavior phenotype, non-suppressible by Hsap\SLK^R1037G.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has abnormal larval locomotory behavior phenotype, non-suppressible by Hsap\SLK^S781Y.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has decreased rate of adult locomotory behavior phenotype, non-suppressible by Hsap\SLK^E472term.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has decreased rate of adult locomotory behavior phenotype, non-suppressible by Hsap\SLK^R1037G.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^elav.PLu, Slik^HMC03770 has larval ventral nerve cord phenotype, suppressible by Hsap\SLK^UAS.cAa, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has NMJ bouton | larval stage phenotype, suppressible by Hsap\SLK^UAS.cAa, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

NOT suppressed by

Statement

Reference

Scer\GAL4^elav.PLu, Slik^HMC03770 has larval ventral nerve cord phenotype, non-suppressible by Hsap\SLK^E472term.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has larval ventral nerve cord phenotype, non-suppressible by Hsap\SLK^Q538term.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has larval ventral nerve cord phenotype, non-suppressible by Hsap\SLK^R1037G.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has larval ventral nerve cord phenotype, non-suppressible by Hsap\SLK^S781Y.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has NMJ bouton | larval stage phenotype, non-suppressible by Hsap\SLK^E472term.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has NMJ bouton | larval stage phenotype, non-suppressible by Hsap\SLK^S781Y.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has NMJ bouton | larval stage phenotype, non-suppressible by Hsap\SLK^Q538term.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Scer\GAL4^elav.PLu, Slik^HMC03770 has NMJ bouton | larval stage phenotype, non-suppressible by Hsap\SLK^R1037G.UAS, Scer\GAL4^elav.PLu

(Alabdi et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

55626

y¹ sc^* v¹ sev²¹; P{TRiP.HMC03770}attP40

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Slik^HMC03770

slik^HMC03770

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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