FlyBase Allele Report: Dmel\CkIα[UAS.Tag:HA]

General Information

Symbol

Dmel\CkIα^UAS.Tag:HA

Species

D. melanogaster

Name

FlyBase ID

FBal0294975

Feature type

allele

Associated gene

Dmel\CkIα

Associated Insertion(s)

Carried in Construct

P{UAS-CkIα.HA}

Key Links

Transgenic product class

wild_type

(Nybakken, 2014.2.28)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Nybakken, 2014.2.28)

Mutagen

in vitro construct

(Nybakken, 2014.2.28)

Progenitor genotype

Carried in construct

P{UAS-CkIα.HA}

Cytology

Description

UAS regulatory sequences drive expression of CkIα tagged at the C-terminal end with 3xTag:HA.

(Nybakken, 2014.2.28)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

CkIα

Tagged with

Tag:HA

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates neurodevelopmental disorder with regression, abnormal movements, loss of speech, and seizures

modeled by Pits^{MI02926-DH.PT-GFSTF.1}, slmb^UAS.vhhGFP4

(Marcogliese et al., 2022)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Scer\GAL4^Act.PU/CkIα^UAS.Tag:HA is a non-enhancer of decreased cell number | adult stage | somatic clone phenotype of dind^Δ9

(Ren et al., 2022)

CkIα^UAS.Tag:HA, Scer\GAL4^esg.PU is a non-enhancer of decreased cell number | adult stage phenotype of Scer\GAL4^esg.PU, dind^{RNAi.UAS.RNAi}

(Ren et al., 2022)

NOT Suppressor of

Statement

Reference

Scer\GAL4^Act.PU/CkIα^UAS.Tag:HA is a non-suppressor of decreased cell number | somatic clone | adult stage phenotype of dind^Δ9

(Ren et al., 2022)

CkIα^UAS.Tag:HA, Scer\GAL4^esg.PU is a non-suppressor of decreased cell number | adult stage phenotype of Scer\GAL4^esg.PU, dind^{RNAi.UAS.RNAi}

(Ren et al., 2022)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Scer\GAL4^Act.PU/CkIα^UAS.Tag:HA is a non-enhancer of adult posterior midgut epithelium | somatic clone phenotype of dind^Δ9

(Ren et al., 2022)

CkIα^UAS.Tag:HA, Scer\GAL4^esg.PU is a non-enhancer of adult posterior midgut epithelium phenotype of Scer\GAL4^esg.PU, dind^{RNAi.UAS.RNAi}

(Ren et al., 2022)

NOT Suppressor of

Statement

Reference

Scer\GAL4^Act.PU/CkIα^UAS.Tag:HA is a non-suppressor of adult posterior midgut epithelium | somatic clone phenotype of dind^Δ9

(Ren et al., 2022)

CkIα^UAS.Tag:HA, Scer\GAL4^esg.PU is a non-suppressor of adult posterior midgut epithelium phenotype of Scer\GAL4^esg.PU, dind^{RNAi.UAS.RNAi}

(Ren et al., 2022)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

55067

w^*; P{UAS-CkIα.HA}1/CyO

55068

w^*; P{UAS-CkIα.HA}5/TM3, Sb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CkIα^{Scer\UAS.T:Ivir\HA1}

CkIα^UAS.Tag:HA

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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