FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\seq9.17
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General Information
Symbol
Dmel\seq9.17
Species
D. melanogaster
Name
FlyBase ID
FBal0295282
Feature type
allele
Associated gene
Dmel\seq
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
gamma ray
(Dean et al., 2013)
Progenitor genotype
Cytology
Description

A 23 base-pair deletion within the second coding exon of seq that causes a frameshift resulting in 260novel amino acids following Q561, but leaving the zinc finger domains intact.

(Dean et al., 2013)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:13,181,896..13,181,918 [-]
Comment:

Estimated boundaries of a 23 bp deletion that causes a frameshift in the second exon of seq. The frameshift introduces 260 novel amino acids after residue Q561.

(Dean et al., 2013)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      seq9.17/seq[+] is an enhancer of partially lethal - majority live phenotype of trioM89/trioS036810

      (Dean et al., 2013)

      seq9.17/seq[+] is an enhancer of some die during P-stage phenotype of trioM89/trioS036810

      (Dean et al., 2013)
      Other
      Statement
      Reference

      seq9.17/seq[+], trioM89/trioS036810 has abnormal feeding behavior phenotype

      (Dean et al., 2013)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      seq9.17 dominantly exacerbates the pre-pupal lethality of trioM89/trioS036810. However, survival to third instar larvae is indistinguishable between wild-type and the mutants. The seq9.17/+; trioM89/trioS036810 larvae retain the forager-like feeding behaviour at a time (90-93 hours after hatching) when their siblings and all control larvae have already transitioned to wanderers.

      (Dean et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      seq9.17
      (Dean et al., 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)