FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\nAChRα4UAS.cSa
Open Close
General Information
Symbol
Dmel\nAChRα4UAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Shi
FlyBase ID
FBal0295292
Feature type
allele
Associated gene
Dmel\nAChRα4
Associated Insertion(s)
Carried in Construct
PBac{UAS-nAChRα4.S}
Key Links
Transgenic product class
cDNA
(Shi et al., 2014)
wild_type
(Shi et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Shi et al., 2014)
wild_type
(Shi et al., 2014)
Mutagen
in vitro construct
(Shi et al., 2014)
Progenitor genotype
Carried in construct
PBac{UAS-nAChRα4.S}
Cytology
Description

UAS regulates expression of a full-length nAChRα4 cDNA.

(Shi et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
nAChRα4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scer\GAL4nAChRα4.ryeP-mediated expression of nAChRα4Scer\UAS.cSa does not increase sleep length in a wild type background.

      (Shi et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      nAChRα4UAS.cSa/Scer\GAL4nAChRα4.ryeP partially rescues nAChRα4rye

      (Shi et al., 2014)
      Comments

      Scer\GAL4nAChRα4.ryeP-mediated expression of nAChRα4Scer\UAS.cSa partially rescues the nAChRα4rye phenotype and restores total sleep to levels seen in nAChRα4rye heterozygotes.

      (Shi et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      nAChRα4Scer\UAS.cSa
      nAChRα4UAS.cSa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Shi
      Secondary FlyBase IDs
        References (1)