FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\UtxΔ95
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General Information
Symbol
Dmel\UtxΔ95
Species
D. melanogaster
Name
FlyBase ID
FBal0295295
Feature type
allele
Associated gene
Dmel\Utx
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Zhang et al., 2013)
Mutagen
Delta2-3 transposase
(Zhang et al., 2013)
Progenitor genotype
P{GSV6}UtxGS10564
(Zhang et al., 2013)
Cytology
Description

Imprecise excision of P{GSV6}UtxGS10564, resulting in a 1,691 bp deletion of 5 exons of Utx, from ggttatttgtatgtatgtat to taaaccaatcagtgggcaat.

(Zhang et al., 2013)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2L:10,275,091..10,276,782 [-]
Comment:

1,691 bp deletion resulting from the imprecise excision of P{GSV6}UtxGS10564, extends from ggttatttgtatgtatgtat to taaaccaatcagtgggcaat.

(Zhang et al., 2013)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      UtxΔ95 homozygotes only rarely survive to adults.

      UtxΔ95/Utx1 animals can develop into adults, which show no detectable morphological defects.

      UtxΔ95/Utx1 embryos show a markedly lower hatching rate compared to wild type. Treatment with 10 Gy of ionizing radiation reduces the hatching rate of UtxΔ95/Utx1 embryos to a greater extent than that of wild type. In contrast, the hatching rate of mutant embryos is not significantly different to wild type after UV radiation exposure.

      (Zhang et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      UtxΔ95
      utxΔ95
      (Zhang et al., 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)