FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\hid-FRT.UAS.cSa
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General Information
Symbol
Dmel\hid-FRT.UAS.cSa
Species
D. melanogaster
Name
FlyBase ID
FBal0295489
Feature type
allele
Associated gene
Dmel\hid
Associated Insertion(s)
Carried in Construct
P{UAS(-FRT)hid}
Key Links
Transgenic product class
wild_type
(Shang et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Shang et al., 2008)
Mutagen
FLPase
(Shang et al., 2008)
Progenitor genotype
hidFRT.UAS.cSa
(Shang et al., 2008)
Carried in construct
P{UAS(-FRT)hid}
Cytology
Description

The FRT cassette has been excised, allowing expression of the hid coding region under the control of UASt regulatory sequences.

(Shang et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
hid
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies in which W-FRT.Scer\UAS.cSa is expressed under the control of Scer\GAL4dimm-929 in the large ventral lateral neurons (l-LNvs) of the brain (Scer\FLP1Ecol\lexAop.cSa protein produced by expression of Ecol\lexAPdf.cSa.T:Hsim\VP16 has been used to generate W-FRT.Scer\UAS.cSa from its WScer\FRT.Scer\UAS.cSa progenitor in a subset of the Ecol\lexAPdf.cSa.T:Hsim\VP16 expressing cells) show a decrease in the number of l-LNvs compared to controls (from 10 to an average of 2-4 cells per hemisphere). Females have a consistent and significant decrease in daytime activity and a reciprocal increase in daytime sleep compared to controls. This phenotype is more obvious under constant light conditions and disappears under constant darkness conditions.

      (Shang et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      W-FRT.Scer\UAS.cSa
      hid-FRT.Scer\UAS.cSa
      hid-FRT.UAS.cSa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)