FB2026_02 , released June 18, 2026
Allele: Ecol\lexAVP16.Pdf
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General Information
Symbol
Ecol\lexAVP16.Pdf
Species
E. coli
Name
FlyBase ID
FBal0295486
Feature type
allele
Associated gene
Ecol\lexA
Associated Insertion(s)
Carried in Construct
P{Pdf-lexA-VP16.S}
Also Known As
Pdf-LexA
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Shang et al., 2008)
Progenitor genotype
Carried in construct
P{Pdf-lexA-VP16.S}
Cytology
Description

A 2.4kb Pdf promoter fragment drives expression of a lexA::VP16 driver. SV40 3'UTR sequences are present.

(Shang et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
Pdf
Encoded product / tool
lexA::VP16
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      larval stage
      larval s-LNv Pdf neuron
      (Yao et al., 2012)
      third instar larval stage
      LNv neuron
      (Qin et al., 2019)
      pharate adult stage
      s-LNv Pdf neuron
      (Selcho et al., 2017)
      adult stage
      s-LNv Pdf neuron
      (Cavanaugh et al., 2014, Yao et al., 2012)
      l-LNv neuron
      (Li et al., 2018, Yao et al., 2012)
      adult s-LNv neuron
      (Li et al., 2018)
      Additional Information
      Statement
      Reference

      Drives expression in LNv Pdf neurons.

      (FlyBase Curators, 2017)

      GFP reconstitution across synaptic partners (GRASP) using EcollexAPdf.cSa.T:HsimVP16 in combination with ScerGAL4Clk.4.1M shows expression at the most distal part of s-LNv dorsal projections indicating a connection of Pdf positive sLNv neurons to Clk positive DN1p neurons.

      (Cavanaugh et al., 2014)
       
      Marker for
      Reflects expression of
      Pdf
      (Cavanaugh et al., 2014, Yao et al., 2012)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Not the same as Ecol\lexA[Pdf. T:Hsim \VP16] (FBal0280997) - no author overlap and both papers clearly describe making their own Pdf-lexA constructs themselves. gm140409.

      (Shang et al., 2008)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ecol\lexAPdf.cSa.T:Hsim\VP16
      Ecol\lexAVP16.Pdf
      Name Synonyms
      Secondary FlyBase IDs
        References (20)