FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\RecQ5GS9658
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General Information
Symbol
Dmel\RecQ5GS9658
Species
D. melanogaster
Name
FlyBase ID
FBal0295628
Feature type
allele
Associated gene
Dmel\RecQ5
Associated Insertion(s)
P{GSV6}RecQ5GS9658
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GSV6}RecQ5GS9658
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{GSV6}
    Regulatory region(s)
    UASt
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 1 )
        Disease
        Interaction
        References
        ameliorates  neurodegenerative disease
        modeled by Hsap\ATXN182Q.UAS
        (Barclay et al., 2014)
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhancer of
        Suppressor of
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference

        Expression of RecQ5GS9658 suppresses the reduction in eclosion rate seen when Hsap\ATXN182Q.Scer\UAS is expressed under the control of Scer\GAL4RapGAP1-OK6 (calculated using the Virtual Eclosion Rate (VER) method). The shortened lifespan is enhanced.

        (Barclay et al., 2014)
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        RecQ5GS9658
        Name Synonyms
        Secondary FlyBase IDs
          References (1)