FB2026_02 , released June 18, 2026
Allele: Dmel\sei3'UTR.UAS
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General Information
Symbol
Dmel\sei3'UTR.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0295772
Feature type
allele
Associated gene
Dmel\sei
Associated Insertion(s)
Carried in Construct
P{UAS-sei.3'UTR}
Key Links
Transgenic product class
wild_type
(Zheng et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Zheng et al., 2014)
Mutagen
in vitro construct
(Zheng et al., 2014)
Progenitor genotype
Carried in construct
P{UAS-sei.3'UTR}
Cytology
Description

UASt regulatory sequences drive expression of the sei-PA variant (NP_476713) plus its 3'UTR.

(Zheng et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
sei
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing sei3'UTR.Scer\UAS under the control of Scer\GAL4elav-C155 are less sensitive than wild-type flies to acute heat stress, with the time to total paralysis being significantly longer in the mutant flies than in wild-type controls.

      (Zheng et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4elav-C155/sei3'UTR.UAS rescues seiHP21840

      (Zheng et al., 2014)
      Comments

      The decreased time to total paralysis in response to heat stress which is seen in seiHP21840 flies is fully rescued by expression of sei3'UTR.Scer\UAS under the control of Scer\GAL4elav-C155.

      (Zheng et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      sei3'UTR.Scer\UAS
      sei3'UTR.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)