FB2026_02 , released June 18, 2026
Allele: Hsap\PDXKTub.Tag:HA
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General Information
Symbol
Hsap\PDXKTub.Tag:HA
Species
H. sapiens
Name
FlyBase ID
FBal0295828
Feature type
allele
Associated gene
Hsap\PDXK
Associated Insertion(s)
Carried in Construct
P{tub-Hsap\PDXK.HA1}
Key Links
Transgenic product class
cDNA
(Marzio et al., 2014)
wild_type
(Marzio et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Marzio et al., 2014)
wild_type
(Marzio et al., 2014)
Mutagen
in vitro construct
(Marzio et al., 2014)
Progenitor genotype
Carried in construct
P{tub-Hsap\PDXK.HA1}
Cytology
Description

Tubulin promoter sequences drive expression of a 940bp Hsap\PDXK cDNA tagged at the 3' end with 3XTag:HA.

(Marzio et al., 2014)
Allele components
Component
Use(s)
Encoded product / tool
Hsap\PDXK
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Hsap\PDXKTub.Tag:HA is a suppressor of lethal phenotype of Pdxk1

      (Marzio et al., 2014)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Hsap\PDXKTub.Tag:HA in the Pdxk1 heterozygote background does not lead to any chromosomal aberrations in third instar larval neuroblasts when compared to controls.

      (Mascolo et al., 2019)
      Xenogenetic Interactions
      Statement
      Reference

      Expression of Hsap\PDXKtub.T:Ivir\HA1 rescues the high frequency of chromosome aberrations compared to controls seen in Pdxk1 mutants when exposed to colchicine. The lethality is also rescued.

      Expression of Hsap\PDXKtub.T:Ivir\HA1 rescues the high frequency of chromosome aberrations compared to controls seen in Pdxk2 mutants when exposed to colchicine.

      (Marzio et al., 2014)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Hsap\PDXKTub.Tag:HA
      Hsap\PDXKtub.T:Ivir\HA1
      Name Synonyms
      Secondary FlyBase IDs
        References (2)