FB2026_02 , released June 18, 2026
Allele: Dmel\Nab2fl.UAS.Tag:FLAG
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General Information
Symbol
Dmel\Nab2fl.UAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0295871
Feature type
allele
Associated gene
Dmel\Nab2
Associated Insertion(s)
Carried in Construct
P{UAS-Flag-Nab2}
Key Links
Transgenic product class
wild_type
(Kelly et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Kelly et al., 2014)
Mutagen
in vitro construct
(Kelly et al., 2014)
Progenitor genotype
Carried in construct
P{UAS-Flag-Nab2}
Cytology
Description

UAS regulatory sequences drive expression of Nab2 coding sequences tagged at the N-terminal with Tag:FLAG.

(Kelly et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Nab2
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4elav-C155/Nab2fl.UAS.Tag:FLAG rescues Nab2ex3

      (Kelly et al., 2014)

      Nab2fl.UAS.Tag:FLAG rescues Nab2ex3

      (Kelly et al., 2014)
      Comments

      Expression of Nab2fl.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4elav-C155 rescues eclosion rates in Nab2ex3 mutants from ~3% to 93%. The presence of Nab2fl.Scer\UAS.T:Zzzz\FLAG alone (i.e. without a Scer\GAL4 driver) increases eclosion rates from 3% to 39% in Nab2ex3 homozygous mutants.

      Expression of Nab2fl.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4elav-C155 restores normal wing posture in eclosed Nab2ex3 homozygous mutants. Thoracic bristle kinking is not rescued by pan-neuronal expression of Nab2Scer\UAS.T:Zzzz\FLAG.

      (Kelly et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Nab2fl.Scer\UAS.T:Zzzz\FLAG
      Nab2fl.UAS.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (1)