FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\DroncUAS.Tag:FLAG
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General Information
Symbol
Dmel\DroncUAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0295940
Feature type
allele
Associated gene
Dmel\Dronc
Associated Insertion(s)
Carried in Construct
P{UAS-Dronc.FLAG}
Also Known As
UAS-Dronc, UAS-Flag-Dronc
Key Links
Transgenic product class
wild_type
(Yang et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Yang et al., 2010)
Mutagen
in vitro construct
(Yang et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-Dronc.FLAG}
Cytology
Description

UAS regulatory sequences drive expression of wild-type Dronc tagged with Tag:FLAG.

(Yang et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Dronc
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of NcScer\UAS.T:Zzzz\FLAG in the developing eye under the control of Scer\GAL4GMR.PF induces apoptosis. Expression of two copies of NcScer\UAS.T:Zzzz\FLAG results in eye ablation, with the mosaic phenotype resulting from the death of eye pigment cells.

      Overexpression of NcScer\UAS.T:Zzzz\FLAG with the pan-neural driver Scer\GAL4elav-C155 causes inadequate wing expansion, even when only one copy of NcScer\UAS.T:Zzzz\FLAG is present.

      Newly eclosed flies expressing NcScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4elav-C155 remain untanned in their abdomen after incubation at 25[o]c for 3 hours, whereas their control siblings exhibit normal maturation as evidenced by their darker abdomen, indicating a delayed maturation.

      (Yang et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Down-regulation of Men through expression of MenKK107809 under the control of Scer\GAL4elav-C155 aggravates the wing expansion defects induced by Scer\GAL4elav-C155-driven expression of NcScer\UAS.T:Zzzz\FLAG.

      (Yang et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference

      Co-expression of BacA\p35Scer\UAS.cHa with NcScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4elav-C155 significantly restores bursicon levels in haemolymph and reduces the wing expansion defects regardless of the expression levels of Nc.

      (Yang et al., 2010)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      DroncScer\UAS.T:Zzzz\FLAG
      DroncUAS.Tag:FLAG
      NcScer\UAS.T:Zzzz\FLAG
      NcScer\UAS.cYa
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0267525
      • FBal0264881
      References (7)