FB2026_02 , released June 18, 2026
Allele: Dmel\PolHUASp.Tag:HA
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General Information
Symbol
Dmel\PolHUASp.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0296081
Feature type
allele
Associated gene
Dmel\PolH
Associated Insertion(s)
Carried in Construct
P{UASp-HA-PolH}
Key Links
Transgenic product class
cDNA
(Wallace et al., 2014)
wild_type
(Wallace et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Wallace et al., 2014)
wild_type
(Wallace et al., 2014)
Mutagen
in vitro construct
(Wallace et al., 2014)
Progenitor genotype
Carried in construct
P{UASp-HA-PolH}
Cytology
Description

UASp regulatory sequences drive expression of a DNApol-η cDNA that is tagged with Tag:HA.

(Wallace et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
PolH
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The developmental delay, mitotic spindle defects and reduced hatching rate of embryos derived from homozygous nopo5-SZ-3004 females is suppressed by expression of DNApol-ηScer\UAS.P\T.T:Ivir\HA1 under the control of Scer\GAL4nos.UTR.T:Hsim\VP16.

      (Wallace et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4VP16.nanos.UTR/PolHUASp.Tag:HA rescues PolHExc2.15

      (Wallace et al., 2014)

      Scer\GAL4VP16.nanos.UTR/PolHUASp.Tag:HA rescues Df(3L)BSC284/PolHExc2.15

      (Wallace et al., 2014)
      Comments

      Expression of DNApol-ηScer\UAS.P\T.T:Ivir\HA1 under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 suppresses the increased sensitivity to UV irradiation and abnormal spindle phenotype seen in embryos derived from homozygous DNApol-ηExc2.15 or DNApol-ηExc2.15/Df(3L)BSC284 females.

      (Wallace et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      DNApol-ηScer\UAS.P\T.T:Ivir\HA1
      DNApol-ηUASp.Tag:HA
      PolHUASp.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)