FlyBase Allele Report: Dmel\Tie[Exel9028]

General Information

Symbol

Dmel\Tie^Exel9028

Species

D. melanogaster

Name

FlyBase ID

FBal0296367

Feature type

allele

Associated gene

Dmel\Tie

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Caused by aberration

Df(3L)Exel9028

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

radiation sensitive | dominant

(Bilak et al., 2014)

viable

(Bilak et al., 2014)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Tie^Exel9028 has radiation sensitive | dominant phenotype, suppressible by mir-ban^as.A.UAS

(Bilak et al., 2014)

Enhancer of

Statement

Reference

Tie^Exel9028/Tie[+] is an enhancer of radiation sensitive phenotype of mir-ban^L1170a

(Bilak et al., 2014)

Suppressor of

Statement

Reference

Tie^Exel9028, Scer\GAL4^ptc-559.1 is a suppressor of radiation resistant | cell non-autonomous phenotype of E2f1^RNAi.UAS.cJa, Scer\GAL4^ptc-559.1

(Bilak et al., 2014)

Other

Statement

Reference

E2f1^RNAi.UAS.cJa, Scer\GAL4^ptc-559.1, Tie^Exel9028, mir-ban^as.A.UAS has radiation resistant | cell non-autonomous phenotype

(Bilak et al., 2014)

Phenotype Manifest In

Suppressor of

Statement

Reference

Tie^Exel9028, Scer\GAL4^ptc-559.1 is a suppressor of wing disc | cell non-autonomous phenotype of E2f1^RNAi.UAS.cJa, Scer\GAL4^ptc-559.1

(Bilak et al., 2014)

Other

Statement

Reference

E2f1^RNAi.UAS.cJa, Scer\GAL4^ptc-559.1, Tie^Exel9028, mir-ban^as.A.UAS has wing disc | cell non-autonomous phenotype

(Bilak et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

One copy of Tie^Exel9028 attenuates the protective effect on surrounding cells seen when cell death is initiated through expression of E2f1^{dsRNA.Scer\UAS.cJa} under the control of Scer\GAL4^ptc-559.1. Co-expressing ban^A.Scer\UAS restores the protective effect.

(Bilak et al., 2014)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Tie^Exel9028

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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