FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Bug22UAS.GFP
Open Close
General Information
Symbol
Dmel\Bug22UAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0296456
Feature type
allele
Associated gene
Dmel\Bug22
Associated Insertion(s)
Carried in Construct
P{UAS-GFP-Bug22}
Key Links
Transgenic product class
wild_type
(Mendes Maia et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Mendes Maia et al., 2014)
Mutagen
in vitro construct
(Mendes Maia et al., 2014)
Progenitor genotype
Carried in construct
P{UAS-GFP-Bug22}
Cytology
Description

UASt regulatory sequences drive expression of Bug22 that is tagged at the N-terminal end with GFP.

(Mendes Maia et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Bug22
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Bug22UAS.GFP/Scer\GAL4JO15 partially rescues Bug22KO

      (Mendes Maia et al., 2014)

      Bug22UAS.GFP/Scer\GAL4DJ684 partially rescues Bug22KO

      (Mendes Maia et al., 2014)

      Bug22UAS.GFP/Scer\GAL4elav.PLu partially rescues Bug22KO

      (Mendes Maia et al., 2014)
      Fails to rescue

      Bug22UAS.GFP/Scer\GAL4Mef2.PR fails to rescue Bug22KO

      (Mendes Maia et al., 2014)

      Bug22UAS.GFP/Scer\GAL4how-24B fails to rescue Bug22KO

      (Mendes Maia et al., 2014)
      Comments

      Expression of Bug22Scer\UAS.T:Avic\GFP under the control of either Scer\GAL4Mef2.PR or Scer\GAL4how-24B fails to rescue any aspect of the Bug22KO wing and uncoordinated phenotypes.

      Expression of Bug22Scer\UAS.T:Avic\GFP under the control of Scer\GAL4JO15 partially rescues the Bug22KO wing phenotype, but the rescued animals still show defects in locomotion and climbing ability.

      Expression of Bug22Scer\UAS.T:Avic\GFP under the control of either Scer\GAL4DJ684 or Scer\GAL4elav.PLu almost completely rescues the wing and uncoordinated phenotypes of Bug22KO flies.

      (Mendes Maia et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Bug22Scer\UAS.T:Avic\GFP
      Bug22UAS.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)