FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\SkpAUAS.OB
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General Information
Symbol
Dmel\SkpAUAS.OB
Species
D. melanogaster
Name
FlyBase ID
FBal0297291
Feature type
allele
Associated gene
Dmel\SkpA
Associated Insertion(s)
Carried in Construct
P{UAS-SkpA.OB}
Key Links
Transgenic product class
wild_type
(Fereres et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Fereres et al., 2013)
Mutagen
in vitro construct
(Fereres et al., 2013)
Progenitor genotype
Carried in construct
P{UAS-SkpA.OB}
Cytology
Description

UAS regulates expression of SkpA.

(Fereres et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
SkpA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scer\GAL4Dll.PU- or Scer\GAL4rn.PU-mediated expression of SkpAScer\UAS.OB interferes with joint formation in the tarsal segments of prothoracic legs.

      Scer\GAL4hh.PU-mediated expression of SkpAScer\UAS.OB reduces apoptosis in the posterior half of the wing disc after irradiation.

      (Fereres et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Scer\GAL4sd.PU/SkpAUAS.OB is a suppressor | partially of wing phenotype of Scer\GAL4sd.PU, rprUTR.UAS.Tag:HA

      (Fereres et al., 2013)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of SkpAScer\UAS.OB partially restores wings to flies expressing rprUTR.Scer\UAS.T:Ivir\HA1 via Scer\GAL4sd.PU.

      (Fereres et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      SkpAScer\UAS.OB
      SkpAUAS.OB
      Name Synonyms
      Secondary FlyBase IDs
        References (1)