FlyBase Allele Report: Dmel\otk[A1]

General Information

Symbol

Dmel\otk^A1

Species

D. melanogaster

Name

FlyBase ID

FBal0297438

Feature type

allele

Associated gene

Dmel\otk

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

amorphic allele - molecular evidence

Mutagen

FLPase

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Linnemannstöns et al., 2014)

Mutagen

FLPase

(Linnemannstöns et al., 2014)

Progenitor genotype

PBac{PB}c03992

(Linnemannstöns et al., 2014)

P{XP}d01360

(Linnemannstöns et al., 2014)

Cytology

Description

FLP-induced excision of P{XP}d01360 and PBac{PB}c03992 removes the otk coding region.

(Linnemannstöns et al., 2014)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable

(Ripp et al., 2018, Linnemannstöns et al., 2014)

Phenotype Manifest In

Detailed Description

Statement

Reference

otk^A1 homozygotes have no discernable phenotype.

(Ripp et al., 2018)

otk^A1 mutants do not display defects in planar cell polarity in their wings and eyes. There do not appear to be any patterning defects in the embryonic cuticle.

(Linnemannstöns et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

otk^A1/otk^A1 is a non-enhancer of viable phenotype of Ror⁴

(Ripp et al., 2018)

otk^A1/otk^A1 is a non-enhancer of fertile phenotype of Ror⁴

(Ripp et al., 2018)

NOT Suppressor of

Statement

Reference

otk^A1/otk^A1 is a non-suppressor of viable phenotype of Ror⁴

(Ripp et al., 2018)

otk^A1/otk^A1 is a non-suppressor of fertile phenotype of Ror⁴

(Ripp et al., 2018)

Other

Statement

Reference

fz¹⁹, otk^A1 has abnormal planar polarity phenotype

(Linnemannstöns et al., 2014)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Flies double mutant for otk^A1/otk^A1; fz¹⁹/fz¹⁹ are viable but exhibit planar polarity defects.

(Linnemannstöns et al., 2014)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

otk^A1

(Ripp et al., 2018)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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