FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\unkUAS.cARa
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General Information
Symbol
Dmel\unkUAS.cARa
Species
D. melanogaster
Name
FlyBase ID
FBal0298398
Feature type
allele
Associated gene
Dmel\unk
Associated Insertion(s)
Carried in Construct
P{UAS-unk.AR}
Key Links
Transgenic product class
wild_type
(Avet-Rochex et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Avet-Rochex et al., 2014)
Mutagen
in vitro construct
(Avet-Rochex et al., 2014)
Progenitor genotype
Carried in construct
P{UAS-unk.AR}
Cytology
Description

UAS regulatory sequences drive expression of unk coding sequence.

(Avet-Rochex et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
unk
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of unkScer\UAS.cARa in MARCM clones does not delay photoreceptor differentiation.

      (Avet-Rochex et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Enhancer of
      Suppressor of
      NOT Suppressor of
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of hdcScer\UAS.cSa and unkScer\UAS.cARa under the control of Scer\GAL4GMR.PU affects eye development.

      Co-expression of hdcScer\UAS.cSa and unkScer\UAS.cARa under the control of Scer\GAL4GMR.PU in Tsc1Q600X mutant eye clones suppresses the precocious differentiation of R7 and cone cells. Neither the delay in differentiation, nor the rough eye phenotype are due to increased apoptosis.

      (Avet-Rochex et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      unkUAS.cARa/Scer\GAL4GMR.PU rescues unkex24

      (Avet-Rochex et al., 2014)
      Comments

      The R1/6 precocious differentiation phenotype in unkex24 mutant clones is rescued by overexpression of unkScer\UAS.cARa.

      (Avet-Rochex et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      unkScer\UAS.cARa
      unkUAS.cARa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)