FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Ecol\lacZslp1.l.DESE+PESE
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General Information
Symbol
Ecol\lacZslp1.l.DESE+PESE
Species
E. coli
Name
FlyBase ID
FBal0298958
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{slp1-lacZ.l.DESE+PESE}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Prazak et al., 2010, Wang et al., 2010)
Progenitor genotype
Carried in construct
P{slp1-lacZ.l.DESE+PESE}
Cytology
Description

A composite of the slp1 distal early stripe element (DESE) enhancer fragment (-8710 to -6506bp) and the slp1 proximal early stripe element (PESE) enhancer fragment (-3.9 to -1.8kb) fused to basal slp1 promoter sequences from -261 to +121bp drives expression of lacZ (all slp1 coordinates relative to the slp1 transcription start site).

(Prazak et al., 2010)

slp1 sequences from 8.7 to 6.5kb and from 3.9 to 1.8kb upstream of the slp1 promoter followed by a basal promoter segment that spans from 260bp upstream to 121bp downstream of the slp1 transcription start site is fused upstream of Ecol\lacZ.

(Wang et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
slp1
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 6 -- 8
      organism | segment polarity expression pattern
      (Wang et al., 2010)
      Additional Information
      Statement
      Reference

      The slp1 reporter recapitulates the slp1 expression pattern in the segmented part of the embryo at the gastrula stage. The only difference is the lack of a stripe of expression in the anterior head region.

      (Wang et al., 2010)
       
      Marker for
      Reflects expression of
      slp1
      (Wang et al., 2010)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ecol\lacZslp1.8765.3918-P
      Ecol\lacZslp1.DESE+PESE
      Ecol\lacZslp1.l.DESE+PESE
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0246088
      • FBal0248428
      References (3)