FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\MarfUAS.cSa.Tag:HA
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General Information
Symbol
Dmel\MarfUAS.cSa.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0299666
Feature type
allele
Associated gene
Dmel\Marf
Associated Insertion(s)
Carried in Construct
P{UAS-Marf.HA.S}
Also Known As
UAS-Marf
Key Links
Transgenic product class
cDNA
(Sandoval et al., 2014)
wild_type
(Sandoval et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Sandoval et al., 2014)
wild_type
(Sandoval et al., 2014)
Mutagen
in vitro construct
(Sandoval et al., 2014)
Progenitor genotype
Carried in construct
P{UAS-Marf.HA.S}
Cytology
Description

Marf is tagged at its C terminus by a single Tag:HA epitope.

(Rival, 2022.2.18)

UASt regulatory sequences drive expression of the Marf open reading frame (derived from the RE04414 cDNA clone) that is tagged with Tag:HA.

(Sandoval et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Marf
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of MarfUAS.cSa.Tag:HA under the control of Scer\GAL4dome-PG14 leads an increase in crystal cells in the third instar larval lymph gland.

      (Ray et al., 2021)

      The expression of MarfUAS.cSa.Tag:HA under the control of Scer\GAL4NP0001 leads to increased mitochondria content in the intestine 2h after pupariation.

      The clonal expression of MarfUAS.cSa.Tag:HA under the control of Scer\GAL4Act5C.PP in the intestine 2h after pupariation leads to increased mitochondria content.

      (Shen et al., 2021)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      NOT Enhancer of
      Suppressor of
      NOT Suppressor of
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      MarfUAS.cSa.Tag:HA/Scer\GAL4Tub.PU rescues MarfB

      (Sandoval et al., 2014)

      Scer\GAL4Feb36/MarfUAS.cSa.Tag:HA rescues MarfB

      (Sandoval et al., 2014)
      Partially rescues

      MarfUAS.cSa.Tag:HA/Scer\GAL4Marf-CR00323-TG4.0 partially rescues MarfCR00323-TG4.0

      (Lee et al., 2018)

      MarfUAS.cSa.Tag:HA/Scer\GAL4Toll-6-D42 partially rescues MarfB

      (Sandoval et al., 2014)
      Fails to rescue

      MarfUAS.cSa.Tag:HA/Scer\GAL4Mef2.PU fails to rescue MarfB

      (Sandoval et al., 2014)
      Comments

      Expression of MarfScer\UAS.cSa.T:Ivir\HA1 under the control of Scer\GAL4D42 rescues the mitochondrial trafficking defects seen in the axons of MarfB mutant larvae. The increase in bouton number seen at the neuromuscular junction is partially rescued.

      Expression of MarfScer\UAS.cSa.T:Ivir\HA1 under the control of either Scer\GAL4tub.PU or Scer\GAL4Feb36 rescues the increase in bouton number seen at the neuromuscular junction in MarfB larvae, while expression under the control of Scer\GAL4Mef2.PU does not.

      Expression of MarfScer\UAS.cSa.T:Ivir\HA1 under the control of Scer\GAL4Feb36 rescues the reduction in lipid droplet number seen in the ring glands of MarfB wandering third instar larvae.

      (Sandoval et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      MarfScer\UAS.cSa.T:Ivir\HA1
      MarfUAS.cSa.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (16)