FlyBase Allele Report: Dmel\Pgam1[HMC04818]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\Pgam1^HMC04818

General Information

Symbol

Dmel\Pgam1^HMC04818

Species

D. melanogaster

Name

FlyBase ID

FBal0300148

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{TRiP.HMC04818}

Key Links

Genomic Maps

Transgenic product class

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMC04818}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Also carries

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates cancer

modeled by Rbf^HMS03004

(Parkhitko et al., 2021)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression under the control of Scer\GAL4^eya.enh1+E+2 results in rough and misshapen eye phenotype.

(Pletcher et al., 2019)

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Pgam1^HMC04818, Scer\GAL4^Cg.PA has decreased cell size | larval stage phenotype, non-enhanceable by upd3^HMS00646, Scer\GAL4^Cg.PA

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has decreased cell size | larval stage phenotype, non-enhanceable by egr^RNAi.UAS, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has decreased cell size | larval stage phenotype, non-enhanceable by Tace^KK109440, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Suppressed by

Statement

Reference

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has decreased cell size | larval stage phenotype, suppressible by REPTOR^JF02005, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has decreased size | larval stage phenotype, suppressible | partially by REPTOR^JF02005, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

NOT suppressed by

Statement

Reference

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has decreased cell size | larval stage phenotype, non-suppressible by egr^RNAi.UAS, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has decreased cell size | larval stage phenotype, non-suppressible by upd3^HMS00646, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^Cg.PA has decreased cell size | larval stage phenotype, non-suppressible by upd3^HMS00646, Scer\GAL4^Cg.PA

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has decreased cell size | larval stage phenotype, non-suppressible by ImpL2^HMC03863, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has decreased cell size | larval stage phenotype, non-suppressible by Tace^KK109440, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has hypodermal muscle of A1-7 | larval stage phenotype, non-enhanceable by upd3^HMS00646, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^Cg.PA has embryonic/larval fat body | larval stage phenotype, non-enhanceable by upd3^HMS00646, Scer\GAL4^Cg.PA

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has embryonic/larval fat body | larval stage phenotype, non-enhanceable by egr^RNAi.UAS, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has embryonic/larval fat body | larval stage phenotype, non-enhanceable by Tace^KK109440, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Suppressed by

Statement

Reference

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has embryonic/larval fat body | larval stage phenotype, suppressible by REPTOR^JF02005, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has lipid droplet | larval stage phenotype, suppressible | partially by REPTOR^JF02005, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has hypodermal muscle of A1-7 | larval stage phenotype, suppressible by REPTOR^JF02005, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has hypodermal muscle of A1-7 | larval stage phenotype, suppressible | partially by egr^RNAi.UAS, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has hypodermal muscle of A1-7 | larval stage phenotype, suppressible by Tace^KK109440, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has hypodermal muscle of A1-7 | larval stage phenotype, suppressible by ImpL2^HMC03863, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

NOT suppressed by

Statement

Reference

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has embryonic/larval fat body | larval stage phenotype, non-suppressible by upd3^HMS00646, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has hypodermal muscle of A1-7 | larval stage phenotype, non-suppressible by upd3^HMS00646, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^Cg.PA has embryonic/larval fat body | larval stage phenotype, non-suppressible by upd3^HMS00646, Scer\GAL4^Cg.PA

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has embryonic/larval fat body | larval stage phenotype, non-suppressible by egr^RNAi.UAS, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has embryonic/larval fat body | larval stage phenotype, non-suppressible by Tace^KK109440, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Pgam1^HMC04818, Scer\GAL4^apolpp.PU has embryonic/larval fat body | larval stage phenotype, non-suppressible by ImpL2^HMC03863, Scer\GAL4^apolpp.PU

(Rodríguez-Vázquez et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

57503

y¹ sc^* v¹ sev²¹; P{TRiP.HMC04818}attP40

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Pgam1^HMC04818

Pglym78^HMC04818

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections