FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\p38c+tCa
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General Information
Symbol
Dmel\p38c+tCa
Species
D. melanogaster
Name
FlyBase ID
FBal0300970
Feature type
allele
Associated gene
Dmel\p38c
Associated Insertion(s)
Carried in Construct
P{p38c+tCa}
Key Links
Transgenic product class
genomic_DNA
(Chakrabarti et al., 2014)
wild_type
(Chakrabarti et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Chakrabarti et al., 2014)
wild_type
(Chakrabarti et al., 2014)
Mutagen
in vitro construct
(Chakrabarti et al., 2014)
Progenitor genotype
Carried in construct
P{p38c+tCa}
Cytology
Description

A genomic fragment comprising the coding region of p38c with the 3'UTR and 300bp of the upstream sequence.

(Chakrabarti et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
p38c
Encoded product / tool
p38c
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      p38c+tCa rescues p38c7B1

      (Chakrabarti et al., 2014)
      Comments

      Expression of p38c+tCa rescues the susceptibility to Ecc15 and P.entomophila infection seen in p38c7B1 mutant flies. The increased susceptibility to H[[2]]O[[2]] is also rescued. Expression of p38c+tCa restores the increase in lipid droplet size seen in p38c7B1 mutants.

      (Chakrabarti et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      p38c+tCa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)